Concept information
Preferred term
Phosphatidylinositol 4,5-Diphosphate
Type
-
Topical Descriptor
Broader concept
Entry terms
- 4,5-Biphosphate, Phosphatidylinositol
- Phosphatidylinositol 4,5 Biphosphate
- Phosphatidylinositol 4,5-Biphosphate
- Phosphatidylinositol-4,5-Biphosphate
- Phosphatidylinositol Phosphate, PtdIns(4,5)P2
- PtdIns(4,5)P2
- PtdInsP
- PtdInsP2
- PtIns 4,5-P2
Scope note
- A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
History note
- 97; see PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE (NM) 1981-96
In other languages
URI
http://www.yso.fi/onto/mesh/D019269
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