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Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Fanconi Anemia Complementation Group Proteins > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins > BRCA1 Protein
Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > BRCA1 Protein

Preferred term

BRCA1 Protein  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • BRCA1 Gene Product
  • Breast Cancer 1 Gene Product
  • Breast Cancer 1 Protein
  • Breast Cancer Type 1 Susceptibility Protein
  • Ring Finger Protein 53

Scope note

  • The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). It contains an N-terminal RING FINGER DOMAIN and is a PROTEIN PHOSPHATASE 1 regulatory subunit. In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)

History note

  • 97; was BRCA1 PROTEIN (NM) 1994-96

In other languages

URI

http://www.yso.fi/onto/mesh/D019313

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RDF/XML TURTLE JSON-LD Created 6/10/96, last modified 11/23/15