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Concept information

Preferred term

Endothelin-1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Endothelin Type 1

Note

  • /drug eff permitted

Scope note

  • A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)

History note

  • 2004(1997); use ENDOTHELINS 1991-96; for BIG ENDOTHELIN use ENDOTHELIN-1 (NM) 1990-2003; for PREPROENDOLTHELIN use ENDOTHELINS-1 (NM) 1989-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D019332

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