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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2B1
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2B1
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2B1
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2B1
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2B1
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2B1

Preferred term

Cytochrome P-450 CYP2B1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 7 Benzyloxyresorufin O Dealkylase
  • 7-Benzyloxyresorufin O-Dealkylase
  • 7 Pentylresorufin O Depentylase
  • 7-Pentylresorufin O-Depentylase
  • Benzyloxyresorufin O Dealkylase
  • Benzyloxyresorufin O-Dealkylase
  • BROD
  • CYP 2B1
  • CYP2B1
  • Cytochrome P450 2B1
  • O-Dealkylase, Pentoxyresorufin
  • Pentoxyresorufin O Dealkylase
  • Pentoxyresorufin O-Dealkylase
  • PROD

Note

  • do not confuse with other cytochrome P-450 CYP's

Scope note

  • A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.

History note

  • 97; was PENTOXYRESORUFIN O-DEALKYLASE (NM) 1985-96

In other languages

URI

http://www.yso.fi/onto/mesh/D019362

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RDF/XML TURTLE JSON-LD Created 6/13/96, last modified 5/27/16