Concept information
Preferred term
Cytochrome P-450 CYP1A1
Type
-
Topical Descriptor
Broader concept
Entry terms
- 7-Ethoxyresorufin O-Deethylase
- CYP 1A1
- CYP1A1
- CYP1A1 Protein
- Cytochrome P450 IA1
- EROD
- Ethoxyresorufin Dealkylase
- Ethoxyresorufin O-Deethylase
- Ethylresorufin O-Deethylase
Note
- do not confuse with other cytochrome P-450 CYP's
Scope note
- A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
History note
- 97; was ETHOXYRESORUFIN O-DEETHYLASE (NM) 1979-96
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D019363
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