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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2D6
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2D6
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Aryl Hydrocarbon Hydroxylases > Cytochrome P-450 CYP2D6
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2D6
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2D6
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2D6

Preferred term

Cytochrome P-450 CYP2D6  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 2-Hydroxylase, Imipramine
  • 4-Hydroxylase, Debrisoquine
  • 4-Monooxygenase, Debrisoquine
  • CYP 2D6
  • CYP2D6
  • Cytochrome P450 2D6
  • Debrisoquine 4 Hydroxylase
  • Debrisoquine 4-Hydroxylase
  • Debrisoquine 4 Monooxygenase
  • Debrisoquine 4-Monooxygenase
  • Debrisoquine Hydroxylase
  • Hydroxylase, Debrisoquine
  • Imipramine 2 Hydroxylase
  • Imipramine 2-Hydroxylase
  • Monooxygenase, Sparteine
  • P450 2D6, Cytochrome
  • Sparteine Monooxygenase

Scope note

  • A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.

History note

  • 97; was DEBRISOQUINE 4-HYDROXYLASE (NM) 1982-96

In other languages

URI

http://www.yso.fi/onto/mesh/D019389

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RDF/XML TURTLE JSON-LD Created 6/13/96, last modified 5/27/16