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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2E1
Enzymes and Coenzymes > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2E1
... > Amino Acids, Peptides, and Proteins > Proteins > Hemeproteins > Cytochromes > Cytochrome P-450 Enzyme System > Cytochrome P450 Family 2 > Cytochrome P-450 CYP2E1
... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxidoreductases Acting on CH-NH Group Donors > Oxidoreductases, N-Demethylating > Cytochrome P-450 CYP2E1

Preferred term

Cytochrome P-450 CYP2E1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 4 Nitrophenol 2 Hydroxylase
  • 4-Nitrophenol-2-Hydroxylase
  • CYP 2E1
  • CYP2E1
  • CYP IIE1
  • CYPIIE1
  • Cytochrome P450 2E1
  • Cytochrome P-450 (ALC)
  • Cytochrome P 450 IIE1
  • Cytochrome P-450 IIE1
  • Cytochrome P 450 J
  • Cytochrome P-450-J
  • Dimethylnitrosamine N Demethylase
  • Dimethylnitrosamine N-Demethylase
  • N Nitrosodimethylamine Demethylase
  • N-Nitrosodimethylamine Demethylase

Note

  • do not confuse with other cytochrome P-450 CYP's

Scope note

  • An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.

History note

  • 97; was DIMETHYLNITROSAMIME N-DEMETHYLASE (NM) 1972-96 & was 4-NITROPHENOL-2-HYDROXYLASE (NM) 1984-96

In other languages

URI

http://www.yso.fi/onto/mesh/D019392

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RDF/XML TURTLE JSON-LD Created 6/24/96, last modified 5/27/16