Concept information
Preferred term
Cytochrome P-450 CYP11B2
Type
-
Topical Descriptor
Broader concept
Entry terms
- Aldosterone Synthase
- Aldosterone Synthase Cytochrome P-450
- Aldosynthase
- CYP 11B2
- CYP11B2
- Cytochrome P450 11B2
- Cytochrome P450Aldo
- Cytochrome P 450c11AS
- Cytochrome P-450c11AS
- P450c11AS
- Steroid 18 Hydroxylase
- Steroid 18-Hydroxylase
Note
- /antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS
Scope note
- A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.
History note
- 2015 (1979)
In other languages
-
Finnish
-
Swedish
-
Aldosteronsyntas
URI
http://www.yso.fi/onto/mesh/D019405
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