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Concept information

Preferred term

Cytochrome P-450 CYP11B2  

Type

  • Topical Descriptor

Entry terms

  • Aldosterone Synthase
  • Aldosterone Synthase Cytochrome P-450
  • Aldosynthase
  • CYP 11B2
  • CYP11B2
  • Cytochrome P450 11B2
  • Cytochrome P450Aldo
  • Cytochrome P 450c11AS
  • Cytochrome P-450c11AS
  • P450c11AS
  • Steroid 18 Hydroxylase
  • Steroid 18-Hydroxylase

Note

  • /antag: coordinate with CYTOCHROME P-450 ENZYME INHIBITORS

Scope note

  • A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.

History note

  • 2015 (1979)

In other languages

URI

http://www.yso.fi/onto/mesh/D019405

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