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Concept information

Preferred term

Multiple System Atrophy  

Type

  • Topical Descriptor

Entry terms

  • Atrophies, Multisystem
  • Atrophies, Multisystemic
  • Atrophy, Multisystem
  • Atrophy, Multisystemic
  • Multiple System Atrophy Syndrome
  • Multisystem Atrophies
  • Multisystem Atrophy
  • Multisystemic Atrophies
  • Multisystemic Atrophy

Note

  • a specific neurodegenerative syndrome complex; not for atrophy in other systems

Scope note

  • A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)

History note

  • 1998

In other languages

URI

http://www.yso.fi/onto/mesh/D019578

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