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... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Kininogens > Kininogen, High-Molecular-Weight
Biological Factors > Blood Coagulation Factors > Kininogens > Kininogen, High-Molecular-Weight
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Kinins > Kininogens > Kininogen, High-Molecular-Weight
Biological Factors > Intercellular Signaling Peptides and Proteins > Kinins > Kininogens > Kininogen, High-Molecular-Weight
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Kinins > Kininogens > Kininogen, High-Molecular-Weight
... > Biological Factors > Inflammation Mediators > Autacoids > Kinins > Kininogens > Kininogen, High-Molecular-Weight
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Kininogens > Kininogen, High-Molecular-Weight

Preferred term

Kininogen, High-Molecular-Weight  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Fitzgerald Factor
  • High Molecular Weight Kininogen
  • High-Molecular-Weight Kininogen
  • High Molecular Weight Kininogens
  • High-Molecular-Weight Kininogens
  • HMWK
  • Kininogens, High Molecular Weight
  • Kininogens, High-Molecular-Weight

Scope note

  • A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)

History note

  • 98; use KININOGENS 1989-97

In other languages

URI

http://www.yso.fi/onto/mesh/D019679

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