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Concept information

Preferred term

Glycyrrhizic Acid  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Acid, Glycyrrhizinic
  • Glycyrrhizin
  • Glycyrrhizinic Acid

Note

  • do not confuse with GLYCYRRHETINIC ACID

Scope note

  • A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.

History note

  • 98; see GLYCYRRHIZIC ACID (NM) 1976-97

In other languages

URI

http://www.yso.fi/onto/mesh/D019695

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RDF/XML TURTLE JSON-LD Created 6/20/97, last modified 7/8/13