Concept information
Preferred term
Thrombospondin 1
Type
-
Topical Descriptor
Broader concept
Entry terms
- TSP-1
Note
- a membrane glycoprotein
Scope note
- An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
History note
- 98; see THROMBOSPONDIN (NM) 1991-97
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D019700
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