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Concept information

Preferred term

Tissue Inhibitor of Metalloproteinases  

Type

  • Topical Descriptor

Entry terms

  • Metalloproteinase Tissue Inhibitor
  • Proteins, TIMP
  • TIMP Proteins
  • Tissue Inhibitor of Metalloproteinase

Note

  • general or unspecified; prefer specifics

Scope note

  • A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes.

History note

  • 98; see TISSUE INHIBITOR OF METALLOPROTEINASES (NM) 1980-97

In other languages

URI

http://www.yso.fi/onto/mesh/D019714

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RDF/XML TURTLE JSON-LD Created 6/20/97, last modified 7/12/22