Concept information
Preferred term
3-Iodobenzylguanidine
Type
-
Topical Descriptor
Broader concept
Entry terms
- Iobenguane
- meta Iodobenzylguanidine
- meta-Iodobenzylguanidine
- MIBG
- m Iodobenzylguanidine
- m-Iodobenzylguanidine
Scope note
- A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
History note
- 98; use 3-IODOBENZYLGUANIDINE (NM) 1980-97
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D019797
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