Concept information
Preferred term
Simvastatin
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- MK 733
- MK-733
- MK733
- Synvinolin
- Zocor
Scope note
- A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
History note
- 98; use SIMVASTATIN (NM) 1986-97
In other languages
-
Finnish
-
Lipcut
-
Simvastatiini Ennapharma
-
Simvastatin Actavis
-
Simvastatin Arrow
-
Simvastatin Avansor
-
Simvastatin Bluefish
-
Simvastatin Copyfarm
-
Simvastatin Genthon
-
Simvastatin Krka
-
Simvastatin Mylan
-
Simvastatin Orion
-
Simvastatin Pfizer
-
Simvastatin Ranbaxy
-
Simvastatin ratiopharm
-
Simvastatin Teva
-
Zocor
-
Swedish
URI
http://www.yso.fi/onto/mesh/D019821
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}