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Concept information

Preferred term

Proto-Oncogene Proteins c-met  

Type

  • Topical Descriptor

Entry terms

  • c met Proteins
  • c-met Proteins
  • c Met Receptor Tyrosine Kinase
  • c-Met Receptor Tyrosine Kinase
  • Hepatocyte Growth Factor Receptor
  • HGF Receptor
  • met Proto Oncogene Proteins
  • met Proto-Oncogene Proteins
  • MET Proto Oncogene, Receptor Tyrosine Kinase
  • MET Proto-Oncogene, Receptor Tyrosine Kinase
  • MET Receptor Tyrosine Kinase
  • Proto-Oncogene Proteins, met
  • Receptor, Hepatocyte Growth Factor
  • Receptor, HGF
  • Receptor, Scatter Factor
  • Scatter Factor Receptor

Scope note

  • Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.

History note

  • 2006, 1998-1999

In other languages

URI

http://www.yso.fi/onto/mesh/D019859

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