Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
...
Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Preferred term
Proto-Oncogene Proteins c-met
Type
-
Topical Descriptor
Entry terms
- c met Proteins
- c-met Proteins
- c Met Receptor Tyrosine Kinase
- c-Met Receptor Tyrosine Kinase
- Hepatocyte Growth Factor Receptor
- HGF Receptor
- met Proto Oncogene Proteins
- met Proto-Oncogene Proteins
- MET Proto Oncogene, Receptor Tyrosine Kinase
- MET Proto-Oncogene, Receptor Tyrosine Kinase
- MET Receptor Tyrosine Kinase
- Proto-Oncogene Proteins, met
- Receptor, Hepatocyte Growth Factor
- Receptor, HGF
- Receptor, Scatter Factor
- Scatter Factor Receptor
Scope note
- Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consist of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations in the c-met proto-oncogene are associated with papillary renal carcinoma and other neoplasia.
History note
- 2006, 1998-1999
In other languages
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Finnish
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c-met-proto-onkogeeniproteiini
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Swedish
URI
http://www.yso.fi/onto/mesh/D019859
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