Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
src-Family Kinases
Preferred term
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Type
-
Topical Descriptor
Broader concept
Entry terms
- c-lck, Proto-Oncogene Protein
- Kinase, lck
- lck Kinase
- lck, Proto-Oncogene Protein
- p56 lck
- Protein c-lck, Proto-Oncogene
- Protein lck, Proto-Oncogene
- Protein Tyrosine Kinase p56(lck)
- Proto Oncogene Protein c lck
- Proto-Oncogene Protein c-lck
- Proto Oncogene Protein lck
- Proto-Oncogene Protein lck
Scope note
- This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.
History note
- 98; use LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK) (NM) 1988-97
In other languages
-
Finnish
-
lymfosyyttien spesifinen proteiinityrosiinikinaasi p56(lck)
-
Swedish
URI
http://www.yso.fi/onto/mesh/D019860
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