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Concept information

Preferred term

Lymphocyte Specific Protein Tyrosine Kinase p56(lck)  

Type

  • Topical Descriptor

Entry terms

  • c-lck, Proto-Oncogene Protein
  • Kinase, lck
  • lck Kinase
  • lck, Proto-Oncogene Protein
  • p56 lck
  • Protein c-lck, Proto-Oncogene
  • Protein lck, Proto-Oncogene
  • Protein Tyrosine Kinase p56(lck)
  • Proto Oncogene Protein c lck
  • Proto-Oncogene Protein c-lck
  • Proto Oncogene Protein lck
  • Proto-Oncogene Protein lck

Scope note

  • This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.

History note

  • 98; use LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK) (NM) 1988-97

In other languages

URI

http://www.yso.fi/onto/mesh/D019860

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RDF/XML TURTLE JSON-LD Created 7/2/97, last modified 5/21/21