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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > eIF-2 Kinase
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > eIF-2 Kinase
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > eIF-2 Kinase

Preferred term

eIF-2 Kinase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Controlled Repressor, Heme
  • Controlled Repressor, Hemin
  • DAI Protein Kinase
  • Double Stranded RNA Dependent eIF 2 alpha Protein Kinase
  • Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase
  • Double Stranded RNA-Dependent Kinase (dsl)
  • dsRNA Activated Inhibitor
  • dsRNA-Activated Inhibitor
  • DSRNA Dep Protein Kinase
  • DSRNA-Dep Protein Kinase
  • eIF 2alpha Kinase
  • eIF-2alpha Kinase
  • eIF-2alpha Kinase, Heme-Regulated
  • eRF, eIF 2 Recycling Factor
  • eRF, eIF-2 Recycling Factor
  • Eukaryotic Initiation Factor 2alpha Kinase
  • Heme Controlled Inhibitor
  • Heme-Controlled Inhibitor
  • Heme Controlled Repressor
  • Heme Controlled Translational Repressor
  • Heme-Controlled Translational Repressor
  • Heme Regulated eIF 2alpha Kinase
  • Heme-Regulated eIF-2alpha Kinase
  • Hemin Controlled Repressor
  • Hemin Controlled Translational Repressor
  • Hemin-Controlled Translational Repressor
  • Inhibitor, dsRNA-Activated
  • Inhibitor, Heme-Controlled
  • Kinase, DAI Protein
  • Kinase, DSRNA-Dep Protein
  • Kinase, eIF-2alpha
  • Kinase, Heme-Regulated eIF-2alpha
  • Kinase, p65
  • Kinase, p68
  • Kinase, P68 Protein
  • Kinase PKR, Protein
  • Kinase, RNA-Dependent Protein
  • Kinase, Self-Phosphorylating Protein
  • Kinase, TIK
  • p65 Kinase
  • p68 Kinase
  • P68 Protein Kinase
  • PKR, Protein Kinase
  • Protein Kinase, DAI
  • Protein Kinase, DSRNA-Dep
  • Protein Kinase, P68
  • Protein Kinase PKR
  • Protein Kinase, RNA Activated
  • Protein Kinase, RNA-Dependent
  • Protein Kinase, Self-Phosphorylating
  • Repressor, Heme Controlled
  • Repressor, Heme-Controlled Translational
  • Repressor, Hemin Controlled
  • Repressor, Hemin-Controlled Translational
  • RNA Dependent Protein Kinase
  • RNA-Dependent Protein Kinase
  • Self Phosphorylating Protein Kinase
  • Self-Phosphorylating Protein Kinase
  • TIK Kinase
  • Translational Repressor, Heme-Controlled
  • Translational Repressor, Hemin-Controlled

Scope note

  • A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.

History note

  • 98; use EIF-2 KINASE (NM) 1980-97

In other languages

URI

http://www.yso.fi/onto/mesh/D019892

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