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Genetic Phenomena > Mutagenesis > Amino Acid Substitution
Investigative Techniques > Genetic Techniques > Genetic Engineering > Protein Engineering > Amino Acid Substitution

Preferred term

Amino Acid Substitution  

Type

  • Topical Descriptor

Broader concept

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Scope note

  • The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

History note

  • 98

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URI

http://www.yso.fi/onto/mesh/D019943

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