Concept information
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Repetitive Sequences, Nucleic Acid
Interspersed Repetitive Sequences
Retroelements
Short Interspersed Nucleotide Elements
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Repetitive Sequences, Nucleic Acid
Interspersed Repetitive Sequences
Retroelements
Short Interspersed Nucleotide Elements
Preferred term
Alu Elements
Type
-
Topical Descriptor
Broader concept
Entry terms
- Alu Families
- Alu Family
- Alu Repetitive Sequence
- Alu Repetitive Sequences
- Families, Alu
- Family, Alu
- Repetitive Sequence, Alu
- Repetitive Sequences, Alu
- Sequence, Alu Repetitive
- Sequences, Alu Repetitive
Scope note
- The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
History note
- 99; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98
In other languages
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Finnish
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Alu-elementti
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Swedish
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Alu-repetetiv sekvens
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Alu-sekvens
URI
http://www.yso.fi/onto/mesh/D020087
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