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Amino Acids, Peptides, and Proteins > Proteins > Receptors, Drug > Immunophilins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Immunophilins
... > Enzymes and Coenzymes > Enzymes > Isomerases > cis-trans-Isomerases > Peptidylprolyl Isomerase > Immunophilins

Preferred term

Immunophilins  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Immunophilin

Note

  • don't confuse entry term NEUROPHILINS with NEUROPILINS

Scope note

  • Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.

History note

  • 2004(1999); for NEUROPHILIN use VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1997-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D020104

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RDF/XML TURTLE JSON-LD Created 6/10/98, last modified 5/26/23