Concept information
Preferred term
Sirolimus
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Rapamycin
Scope note
- A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
History note
- 99; use SIROLIMUS (NM) 1980-97
In other languages
-
Finnish
-
Rapamune
-
rapamysiini
-
Swedish
-
Rapamune
URI
http://www.yso.fi/onto/mesh/D020123
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