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Concept information

Preferred term

ATP Binding Cassette Transporter, Subfamily B, Member 1  

Type

  • Topical Descriptor

Entry terms

  • ABCB1 Protein
  • Antigen, CD243
  • ATP-Binding Cassette, Sub-Family B, Member 1
  • ATP Binding Cassette Transporter, Sub-Family B, Member 1
  • CD243 Antigen
  • MDR1 Protein
  • Multidrug Resistance Protein 1
  • P Glycoprotein
  • P-Glycoprotein
  • PGY 1 Protein
  • PGY-1 Protein

Note

  • note entry term: ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B is also available

Scope note

  • A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

History note

  • 2019 (1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D020168

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