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Nervous System Diseases > Neurotoxicity Syndromes > MPTP Poisoning
Chemically-Induced Disorders > Poisoning > Neurotoxicity Syndromes > MPTP Poisoning
... > Nervous System Diseases > Central Nervous System Diseases > Movement Disorders > Parkinsonian Disorders > Parkinson Disease, Secondary > MPTP Poisoning
... > Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Basal Ganglia Diseases > Parkinsonian Disorders > Parkinson Disease, Secondary > MPTP Poisoning

Preferred term

MPTP Poisoning  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • MPTP Induced Parkinsonism
  • MPTP-Induced Parkinsonism
  • MPTP Neurotoxicity Syndrome
  • MPTP Neurotoxicity Syndromes
  • Neurotoxicity Syndrome, MPTP
  • Neurotoxicity Syndromes, MPTP
  • Parkinsonism, MPTP-Induced
  • Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Note

  • not for animal models of Parkinson disease induced by MPTP: index MPTP-INDUCED EXPERIMENTAL PARKINSONISM

Scope note

  • A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)

History note

  • 2000

In other languages

URI

http://www.yso.fi/onto/mesh/D020267

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