Concept information
Preferred term
Genes, myb
Type
-
Topical Descriptor
Broader concept
Entry terms
- myb Genes
Scope note
- Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
History note
- 2000; use ONCOGENES 1985-1999
In other languages
-
Finnish
-
c-myb-geeni
-
c-myb-geenit
-
myb-geeni
-
v-myb-geeni
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v-myb-geenit
-
Swedish
-
c-myb gener
-
c-myb proto-onkogener
-
myb onkogener
-
v-myb gener
-
v-myb onkogener
URI
http://www.yso.fi/onto/mesh/D020570
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