Concept information
Preferred term
Genes, sis
Type
-
Topical Descriptor
Broader concept
Entry terms
- sis Genes
Scope note
- Retrovirus-associated DNA sequences (v-sis) originally isolated from the simian sarcoma virus (SSV). The proto-oncogene c-sis codes for a growth factor which is the B chain of PLATELET-DERIVED GROWTH FACTOR. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long arm of chromosome 22.
History note
- 2000; use ONCOGENES 1988-1999
In other languages
-
Finnish
-
c-sis-geeni
-
c-sis-geenit
-
PDGFB-geeni
-
PDGFB-geenit
-
sis-geeni
-
v-sis-geeni
-
v-sis-geenit
-
Swedish
-
c-sis gener
-
c-sis proto-onkogener
-
PDGFB gener
-
sis onkogener
-
v-sis gener
-
v-sis onkogener
URI
http://www.yso.fi/onto/mesh/D020571
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