Concept information
Preferred term
Genes, rel
Type
-
Topical Descriptor
Broader concept
Entry terms
- rel Genes
Scope note
- Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2.
History note
- 2000; use ONCOGENES 1988-1999
In other languages
-
Finnish
-
c-rel-geeni
-
c-rel-geenit
-
rel-geeni
-
v-rel-geeni
-
v-rel-geenit
-
Swedish
-
c-rel gener
-
c-rel proto-onkogener
-
rel onkogener
-
v-rel gener
-
v-rel onkogener
URI
http://www.yso.fi/onto/mesh/D020573
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