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... > Amino Acids, Peptides, and Proteins > Proteins > Ribosomal Proteins > Peptide Elongation Factors > GTP Phosphohydrolase-Linked Elongation Factors > Peptide Elongation Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > GTP-Binding Proteins > GTP Phosphohydrolase-Linked Elongation Factors > Peptide Elongation Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > GTP-Binding Proteins > GTP Phosphohydrolase-Linked Elongation Factors > Peptide Elongation Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > GTP-Binding Proteins > GTP Phosphohydrolase-Linked Elongation Factors > Peptide Elongation Factor 1
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Acid Anhydride Hydrolases > GTP Phosphohydrolases > GTP-Binding Proteins > GTP Phosphohydrolase-Linked Elongation Factors > Peptide Elongation Factor 1

Preferred term

Peptide Elongation Factor 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • EF 1
  • EF-1
  • EF 1H
  • EF-1H
  • Elongation Factor 1

Scope note

  • Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.

History note

  • 2000; for ELONGATION FACTOR 1 use PEPTIDE ELONGATION FACTOR 1 (NM) 1980-1999; for ELONGATION FACTOR 1GAMMA use PEPTIDE ELONGATION FACTOR 1 (NM) 1994-1999

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URI

http://www.yso.fi/onto/mesh/D020648

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