Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > GTP-Binding Protein Regulators > GTPase-Activating Proteins > RGS Proteins
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > GTP-Binding Protein Regulators > GTPase-Activating Proteins > RGS Proteins

Preferred term

RGS Proteins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Regulators of G Protein Signaling Proteins
  • Regulators of G-Protein Signaling Proteins
  • RGS Protein (G-Protein Signaling)

Note

  • do not confuse with GTP-BINDING PROTEIN REGULATORS; not the same as RGS tripeptide

Scope note

  • A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form.

History note

  • 2000; for RGS PROTEIN (G-PROTEIN SIGNALING) use GTPASE-ACTIVATING PROTEINS (NM) 1997-1999

In other languages

URI

http://www.yso.fi/onto/mesh/D020710

Download this concept:

RDF/XML TURTLE JSON-LD Created 11/3/99, last modified 11/24/15