Concept information
Nervous System Diseases
Nervous System Neoplasms
Paraneoplastic Syndromes, Nervous System
Myasthenia Gravis
...
Neoplasms by Site
Nervous System Neoplasms
Paraneoplastic Syndromes, Nervous System
Myasthenia Gravis
Nervous System Diseases
Neurodegenerative Diseases
Paraneoplastic Syndromes, Nervous System
Myasthenia Gravis
Immune System Diseases
Autoimmune Diseases
Autoimmune Diseases of the Nervous System
Myasthenia Gravis
...
Models, Theoretical
Models, Biological
Disease Models, Animal
Nervous System Autoimmune Disease, Experimental
Investigative Techniques
Models, Animal
Disease Models, Animal
Nervous System Autoimmune Disease, Experimental
Preferred term
Myasthenia Gravis, Autoimmune, Experimental
Type
-
Topical Descriptor
Broader concept
Entry terms
- Autoimmune Experimental Myasthenia Gravis
- Experimental Myasthenia
- Experimental Myasthenia Gravis
- Experimental Myasthenias
- Myasthenia, Experimental
- Myasthenia Gravis, Autoimmune Experimental
- Myasthenia Gravis, Experimental
- Myasthenia Gravis, Experimental Autoimmune
- Myasthenias, Experimental
Scope note
- Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
History note
- 2005 (2000)
In other languages
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Finnish
-
kokeellinen autoimmuuni myastenia gravis
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Swedish
URI
http://www.yso.fi/onto/mesh/D020720
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