Concept information
Preferred term
Calcium Channels, L-Type
Type
-
Topical Descriptor
Broader concept
Entry terms
- Calcium Channel, Long-Lasting
- Calcium Channel, L-Type
- Calcium Channels, Long-Lasting
- Channel, Long-Lasting Calcium
- Long Lasting Calcium Channel
- Long-Lasting Calcium Channel
- Long Lasting Calcium Channels
- Long-Lasting Calcium Channels
- L Type Calcium Channel
- L-Type Calcium Channel
- L Type Calcium Channels
- L-Type Calcium Channels
- L Type VDCC
- L-Type VDCC
- L Type Voltage Dependent Calcium Channel
- L-Type Voltage-Dependent Calcium Channel
- L Type Voltage Dependent Calcium Channels
- L-Type Voltage-Dependent Calcium Channels
- VDCC, L-Type
Scope note
- Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
History note
- 2000; use L-TYPE CALCIUM CHANNELS (NM) 1993-1999
In other languages
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Finnish
-
dihydropyridiinireseptori
-
dihydropyridiinireseptorit
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L-tyypin kalsiumkanava
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Swedish
URI
http://www.yso.fi/onto/mesh/D020746
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