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Concept information

Preferred term

Calcium Channels, L-Type  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Calcium Channel, Long-Lasting
  • Calcium Channel, L-Type
  • Calcium Channels, Long-Lasting
  • Channel, Long-Lasting Calcium
  • Long Lasting Calcium Channel
  • Long-Lasting Calcium Channel
  • Long Lasting Calcium Channels
  • Long-Lasting Calcium Channels
  • L Type Calcium Channel
  • L-Type Calcium Channel
  • L Type Calcium Channels
  • L-Type Calcium Channels
  • L Type VDCC
  • L-Type VDCC
  • L Type Voltage Dependent Calcium Channel
  • L-Type Voltage-Dependent Calcium Channel
  • L Type Voltage Dependent Calcium Channels
  • L-Type Voltage-Dependent Calcium Channels
  • VDCC, L-Type

Scope note

  • Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and non-excitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.

History note

  • 2000; use L-TYPE CALCIUM CHANNELS (NM) 1993-1999

In other languages

URI

http://www.yso.fi/onto/mesh/D020746

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