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Concept information

Preferred term

Cathepsin C  

Type

  • Topical Descriptor

Entry terms

  • Dipeptidyl Aminopeptidase I
  • Dipeptidyl Peptidase I
  • Dipeptidyl Transferase

Scope note

  • A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.

History note

  • 2010(1981)

In other languages

  • Finnish

  • dipeptidyyliaminopeptidaasi I
  • dipeptidyylipeptidaasi I
  • Swedish

  • Dipeptydylpeptidas I

URI

http://www.yso.fi/onto/mesh/D020789

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