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Concept information

Preferred term

Receptor, Ciliary Neurotrophic Factor  

Type

  • Topical Descriptor

Entry terms

  • Ciliary Neurotrophic Factor Receptor
  • CNTF Receptor
  • Receptor, CNTF

Scope note

  • Cell surface receptors for CILIARY NEUROTROPHIC FACTOR. They are heterotrimeric proteins formed by the association of the CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA SUBUNIT with the LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT and the CYTOKINE RECEPTOR GP130. Although the receptor regulates neuronal development, it is structurally similar to the cytokine receptor for INTERLEUKIN-6; (RECEPTORS, INTERLEUKIN-6).

History note

  • 2000; use RECEPTOR, CILIARY NEUROTROPHIC FACTOR (NM) 1991-1999

URI

http://www.yso.fi/onto/mesh/D020801

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