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... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormone Antagonists > Estrogen Receptor Modulators > Selective Estrogen Receptor Modulators

Preferred term

Selective Estrogen Receptor Modulators  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Estrogen Receptor Modulator, Selective
  • Estrogen Receptor Modulators, Selective
  • Selective Estrogen Receptor Modulator
  • SERM
  • SERMs

Note

  • do not confuse with ESTROGEN RECEPTOR MODULATORS

Scope note

  • A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)

History note

  • 2000

In other languages

URI

http://www.yso.fi/onto/mesh/D020845

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