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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein-Tyrosine Kinases > Receptor Protein-Tyrosine Kinases > Receptor, trkA
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Nerve Growth Factor > Receptor, trkA

Preferred term

Receptor, trkA  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • c-trk, gp140
  • c trk Protein
  • c-trk Protein
  • c-trk, Proto-Oncogene Products
  • gp140 c trk
  • gp140 c-trk
  • gp140(c-TRK)
  • Neurotrophic Tyrosine Kinase Receptor Type 1
  • NTRK1 Receptor
  • p140 trkA
  • p140-trkA
  • Proto Oncogene Products c trk
  • Proto-Oncogene Products c-trk
  • Proto Oncogene Protein trk
  • Proto-Oncogene Protein trk
  • Proto-Oncogene Protein, trk
  • Receptor, Neurotrophic Tyrosine Kinase Type 1
  • Receptor, NTRK1
  • trk1 Transforming Tryrosine Kinase
  • trkA Receptor
  • trk Proto Oncogene Protein
  • trk Proto-Oncogene Protein
  • trk, Proto-Oncogene Protein

Scope note

  • A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.

History note

  • 2000; use RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE(NM) 1990-1999

In other languages

  • trkA-reseptori

    Finnish

  • Gp140(c-TRK)
  • neurotrofisen tyrosiinikinaasi tyyppi 1:n reseptori
  • NTRK1-reseptori
  • proto-onkogeeniproteiini trk
  • trk proto-onkogeeniproteiini
  • trkA-receptor

    Swedish

  • Receptor, trkA

URI

http://www.yso.fi/onto/mesh/D020917

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