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... > Cells > Cellular Structures > Cell Membrane > Cell Membrane Structures > Cell-Matrix Junctions > Hemidesmosomes

Preferred term

Hemidesmosomes  

Type

  • Topical Descriptor

Broader concept

Scope note

  • An anchoring junction of the cell to a non-cellular substrate, similar in morphology to halves of DESMOSOMES. They are composed of specialized areas of the plasma membrane where INTERMEDIATE FILAMENTS bind on the cytoplasmic face to the transmembrane linkers, INTEGRINS, via intracellular attachment proteins, while the extracellular domain of the integrins binds to EXTRACELLULAR MATRIX PROTEINS.

History note

  • 2001

In other languages

URI

http://www.yso.fi/onto/mesh/D022002

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