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Concept information

Preferred term

Tacrolimus Binding Protein 1A  

Type

  • Topical Descriptor

Entry terms

  • FK506 Binding Protein 1
  • FK506-Binding Protein 1
  • FK506 Binding Protein 1A
  • FK506-Binding Protein 1A
  • FKBP 12
  • FKBP-12
  • FKBP12
  • Macrophilin 12
  • Macrophilin-12

Scope note

  • A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS.

History note

  • 2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000

URI

http://www.yso.fi/onto/mesh/D022061

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