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... > Information Science > Information Sources > Information Services > Documentation > Molecular Sequence Data > Amino Acid Sequence > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Amino Acid Sequence > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Globulins > Serum Globulins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Immunoproteins > Immunoglobulins > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Peptides > Peptide Fragments > Immunoglobulin Fragments > Immunoglobulin Fab Fragments > Immunoglobulin Variable Region > Complementarity Determining Regions
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Antigen > Receptors, Antigen, T-Cell > Complementarity Determining Regions

Preferred term

Complementarity Determining Regions  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Complementarity Determining Region
  • Complementarity-Determining Region
  • Complementarity-Determining Regions
  • Hypervariable Region, Immunoglobulin
  • Hypervariable Regions, Immunoglobulin
  • Immunoglobulin Hypervariable Region
  • Immunoglobulin Hypervariable Regions
  • Region, Immunoglobulin Hypervariable
  • Regions, Complementarity-Determining
  • Regions, Immunoglobulin Hypervariable

Scope note

  • Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).

History note

  • 2001; for COMPLEMENTARITY DETERMINING REGION and HYPERVARIABLE REGION use IMMUNOGLOBULIN VARIABLE REGION 1988-2000

In other languages

URI

http://www.yso.fi/onto/mesh/D022801

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