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Concept information

Preferred term

Antimicrobial Cationic Peptides  

Type

  • Topical Descriptor

Entry terms

  • Antimicrobial Peptide, Cationic
  • Antimicrobial Peptides, Cationic
  • Cationic Antimicrobial Peptide
  • Cationic Antimicrobial Peptides
  • Cationic Host Defense Peptides
  • Cationic Proteins, Microbicidal
  • Microbicidal Cationic Proteins
  • Peptide, Cationic Antimicrobial
  • Peptides, Cationic Antimicrobial
  • Proteins, Microbicidal Cationic

Scope note

  • Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.

History note

  • 2001; use ANTIMICROBIAL CATIONIC PEPTIDES (NM) to search MICROBICIDAL CATIONIC PROTEINS 1981-2000

In other languages

URI

http://www.yso.fi/onto/mesh/D023181

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