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Investigative Techniques > Genetic Techniques > Nuclease Protection Assays

Preferred term

Nuclease Protection Assays  

Type

  • Topical Descriptor

Broader concept

Scope note

  • Techniques for measuring specific nucleic acid interaction with another nucleic acid or with a protein by digestion of the non-interacting nucleic acid by various nucleases. After all non-interacting regions are eliminated by nuclease digestion, the protected nucleic acid that remains is analyzed. DNA FOOTPRINTING utilizes this technique to analyze the DNA contact sites of DNA-BINDING PROTEINS.

History note

  • 2001

In other languages

URI

http://www.yso.fi/onto/mesh/D023282

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