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... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Neoplasm > Genes, Tumor Suppressor > Genes, BRCA2
Genetic Phenomena > Inheritance Patterns > Genes, Recessive > Genes, Tumor Suppressor > Genes, BRCA2
... > Genetic Phenomena > Genetic Structures > Genome > Genome Components > Genes > Genes, Recessive > Genes, Tumor Suppressor > Genes, BRCA2

Preferred term

Genes, BRCA2  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • BRCA2 Gene

Note

  • BRCA stands for "BReast CAncer"

Scope note

  • A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)

History note

  • 2002

In other languages

URI

http://www.yso.fi/onto/mesh/D024522

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