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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > BRCA2 Protein
Amino Acids, Peptides, and Proteins > Proteins > Fanconi Anemia Complementation Group Proteins > BRCA2 Protein
Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Tumor Suppressor Proteins > BRCA2 Protein

Preferred term

BRCA2 Protein  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • BRCA2 Gene Product
  • Breast Cancer 2 Gene Product
  • Breast Cancer 2 Protein
  • FANCD1 Protein
  • Fanconi Anemia Complementation Group D1 Protein
  • Fanconi Anemia Group D1 Complementing Protein
  • Fanconi Anemia Group D1 Protein

Scope note

  • A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)

History note

  • 2002; use BRCA2 PROTEIN (NM) 1995-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D024682

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