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Concept information

Preferred term

HMG-Box Domains  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Domain, HMG-1-Box
  • Domains, HMG-1-Box
  • High Mobility Group Box Domains
  • High Mobility Group-Box Domains
  • HMG 1 Box Domain
  • HMG-1-Box Domain
  • HMG-1-Box Domains
  • HMG Box Domain
  • HMG-Box Domain

Note

  • HIGH MOBILITY GROUP PROTEINS is also available

Scope note

  • DNA-binding domains present in proteins of the HMG-box superfamily including the archetypal HMGB PROTEINS, a number of sequence specific TRANSCRIPTION FACTORS, and other DNA-BINDING PROTEINS. The domains consist of 70-80 amino acids that form an L-shaped fold from three alpha-helical segments. The domain has the capacity to recognize and/or induce specific DNA structures and effect the accessibility of the DNA to other proteins involved in transcription, recombination, or DNA repair. (Note that not all HIGH MOBILITY GROUP PROTEINS contain this domain.)

History note

  • 2002

In other languages

URI

http://www.yso.fi/onto/mesh/D024742

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