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Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Picolines > Vitamin B 6

Preferred term

Vitamin B 6  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Vitamin B6

Note

  • /ther use: coordinate with disease /drug ther, not /diet ther

Scope note

  • VITAMIN B 6 refers to several PICOLINES (especially PYRIDOXINE; PYRIDOXAL; & PYRIDOXAMINE) that are efficiently converted by the body to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into PYRIDOXAMINE phosphate. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990). Most of vitamin B6 is eventually degraded to PYRIDOXIC ACID and excreted in the urine.

History note

  • 2002; use PYRIDOXINE 1963-2001

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URI

http://www.yso.fi/onto/mesh/D025101

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