Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Fructokinases > Phosphofructokinases > Phosphofructokinase-1 > Phosphofructokinase-1, Muscle Type

Preferred term

Phosphofructokinase-1, Muscle Type  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 6-Phosphofructokinase, Muscle Type
  • Phosphofructo-1-kinase Isozyme A

Scope note

  • An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.

History note

  • 2002

In other languages

URI

http://www.yso.fi/onto/mesh/D025203

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 7/25/05