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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Phosphofructokinase-2
Enzymes and Coenzymes > Enzymes > Multifunctional Enzymes > Phosphofructokinase-2
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Fructokinases > Phosphofructokinases > Phosphofructokinase-2

Preferred term

Phosphofructokinase-2  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • 6PF2K
  • 6-Phosphofructo-2-kinase
  • ATP-D-Fructose-6-phosphate 2-phosphotransferase
  • Fru-6-P,2-kinase
  • Fructose-6-P,2-kinase
  • Fructose-6-phosphate,2-kinase

Scope note

  • An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.

History note

  • 2002; for 6-PHOSPHOFRUCTO-2-KINASE use PHOSPHOTRANSFERASES (NM) 1993-2001, use PHOSPHOTRANSFERASES, ATP (NM) 1981-1993; for FRUCTOSE-2,6-BISPHOSPATASE use PHOSPHORIC MONOESTER HYDROLASES (NM) 1983-2001; for 6-PHOSPHOFRUCTO-2-KINASE-FRUCTOSE-2,6-BISPHOSPHATASE use FRUCTOSE-BISPHOSPHATASE (NM) 1990-2001, use MULTIENZYME COMPLEXES (NM) 1990-2001, use PHOSPHOFRUCTOKINASE-1 (NM) 1990-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D025481

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