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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Alcohol Oxidoreductases > NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases > 3-Hydroxyacyl CoA Dehydrogenases > Hydroxymethylglutaryl CoA Reductases > Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent

Preferred term

Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent
  • CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl
  • HMG CoA Reductase, NAD Dependent
  • HMG CoA Reductase, NAD-Dependent
  • HMG CoA Reductases, NAD Dependent
  • HMG CoA Reductases, NAD-Dependent
  • Hydroxymethylglutaryl CoA Reductase, NAD Dependent
  • Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
  • NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase

Note

  • do not confuse with HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT

Scope note

  • Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.

History note

  • 2002

In other languages

URI

http://www.yso.fi/onto/mesh/D025781

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