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Amino Acids, Peptides, and Proteins > Proteins > Ubiquitins > Ubiquitin

Preferred term

Ubiquitin  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • APF-1
  • ATP Dependent Proteolysis Factor 1
  • ATP-Dependent Proteolysis Factor 1
  • High Mobility Protein 20
  • HMG-20

Note

  • UBIQUITINS is also available

Scope note

  • A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.

History note

  • 2002; use UBIQUITINS (1985-2001)

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URI

http://www.yso.fi/onto/mesh/D025801

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