Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Bacterial Proteins > DNA Gyrase
... > Enzymes and Coenzymes > Enzymes > Isomerases > DNA Topoisomerases > DNA Topoisomerases, Type II > DNA Gyrase

Preferred term

DNA Gyrase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • DNA-Gyrase

Scope note

  • A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.

History note

  • 2002; use DNA TOPOISOMERASE (ATP-HYDROLYZING) 1994-2001, use DNA GYRASE 1980-1993; for GYRA PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1992-2001; GYRB PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1991-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D027081

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 7/8/13