Concept information
Preferred term
DNA Topoisomerase IV
Type
-
Topical Descriptor
Broader concept
Entry terms
- Topoisomerase IV
- Topo IV
Scope note
- A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.
History note
- 2002; use DNA TOPOISOMERASE IV (NM) 1991-2001
In other languages
-
Finnish
-
DNA-topoisomeraasi IV
-
Swedish
URI
http://www.yso.fi/onto/mesh/D027101
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