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Concept information

Preferred term

DNA Topoisomerase IV  

Type

  • Topical Descriptor

Entry terms

  • Topoisomerase IV
  • Topo IV

Scope note

  • A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.

History note

  • 2002; use DNA TOPOISOMERASE IV (NM) 1991-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D027101

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